CCL2/MCP-1 Recombinant Rabbit mAb (SDT-1737-66)
货号： S0B3361
- 价格： ￥5,690
- 规格：
- 数量：
大包装询价 产品介绍 引用文献(0) 评论(0)
宿主来源
Rabbit抗原名称
CCL2/MCP-1分子别名
C-C motif chemokine 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor (MCAF); Monocyte chemotactic protein 1 (MCP-1); Monocyte secretory protein JE; Small-inducible cytokine A2免疫原
Recombinant ProteinAccession
P13500克隆号
SDT-1737-66抗体类型
Recombinant mAb抗体同种型
IgG应用
Sandwich ELISA反应种属 ?
Hu交叉反应
No cross reactivity with GRO alpha/CXCL1, GRO beta/CXCL2, IL-8
纯化方式
Protein A浓度
2 mg/ml纯度
>95% by HPLC标记
Unconjugated性状
Liquid缓冲体系
PBS pH7.4, 0.03% Proclin 300
储存条件
12 months from date of receipt, 2 to 8 °C as supplied
CCL2, also known as monocyte chemoattractant protein-1 (MCP-1), is a small cytokine belonging to the CC chemokine family. It is primarily secreted by monocytes, macrophages, and dendritic cells, and plays a crucial role in recruiting monocytes, memory T cells, and dendritic cells to sites of inflammation or tissue injury. CCL2 exerts its effects by binding to its receptor, CCR2, and is involved in various biological processes, including leukocyte chemotaxis, regulation of apoptosis, and modulation of immune responses. This chemokine is also implicated in several diseases, such as atherosclerosis, rheumatoid arthritis, cancers and neurodegenerative disorders, due to its role in promoting inflammation and immune cell infiltration. In conclusion, CCL2 is a multifunctional chemokine with significant roles in inflammation, fibrosis, and cancer. Its expression is tightly regulated and serves as a critical mediator of immune cell recruitment and activation. The diagnostic and therapeutic potential of CCL2 makes it a promising target for addressing a wide range of diseases. Further research into the mechanisms of CCL2 regulation and its interactions with the tumor microenvironment will likely yield new insights and therapeutic strategies.
配对推荐
引用文献(0)
评论(0)